- OLIVIE Healthy News - Warning: the statins of anti-cholesterol drugs that are controversial!
- OLIVIE Healthy News -
Warning: the statins of anti-cholesterol drugs that are controversial!
The French controversy over the use of statins, anti-cholesterol drugs used in the prevention of cardiovascular disease, could cause a new medical scandal and be responsible for 1159 deaths in France.
Cholesterol: the impact of stopping statins underestimated
The French controversy over the use of statins, anti-cholesterol drugs used in the prevention of cardiovascular disease, could cause a new medical scandal and be responsible for 1159 deaths in France.
The benefits of statins on the prevention of cardiovascular disease are now well demonstrated. But recently, in France, a controversy has challenged the interest of statins including primary prevention (for patients who have never had cardiovascular events). Indeed, on February 21, Professor Philippe Even, pulmonologist, president of the Necker Institute and Bernard Debré (urologist and French politician) published a controversial book "The Truth About Cholesterol" and stated that "statins would be dangerous, misused, and that their usefulness would be more than doubtful, and that in addition "bad cholesterol" would not exist! "
1159 deaths a year if patients actually stop taking their statins
A study led by the Georges Pompidou Hospital has just evaluated the impact of this controversy on patient compliance with statins.
"The recent controversy on statins could lead to the discontinuation of these treatments in many patients and thus cause the occurrence of many major cardiovascular events," alert the authors, eloquent figures in support.
The researchers studied the observance of the prescription of a sample of 142 patients on statins and extrapolated their results to the French population. In France, this controversy could lead to 4992 major cardiovascular events including 1159 deaths per year if patients actually stop taking their statins.
What is criticized for statins
Statins are among the best-selling drugs in the world. Prescribed to hundreds of millions of patients, they have the ability to lower bad cholesterol (LDL-cholesterol) by 15 to 30%. This "bad" cholesterol is involved in atherosclerosis (which is characterized by a deposit of cholesterol on the artery causing its injury), which is responsible for the majority of cardiovascular diseases (heart attack, stroke ...), and the second cause in France with about 180000 deaths per year.
However, the list of side effects of statins is consistent. It includes liver and digestive disorders, headaches, insomnia, skin allergies, edema, joint pain, tingling, vertigo, memory problems, impotence, hair loss.
"Statins are not necessarily adapted to all patients and their use is not justified when the cardiovascular risk is low," says the French Agency for Health Safety of Health Products (Afssaps). essential for people who have a high cardiovascular risk: those who have coronary artery disease (CAD), arteritis, a history of stroke or diabetes.At them, the taking of statins would reduce 30% mortality rate, "insists Dr. Etienne Puymirat, Georges Pompidou Hospital, Paris, co-author of the study on stopping statins, which has just been published on the site of the Archives of Cardiovascular Disease.
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